Role of the endothelial Protein C Receptor (EPCR), caveolin-1 and b-catenin in the anti-angiogenic action of coagulation Factor X

Abstract

Introduction: Angiogenesis is the formation of new blood vessels from pre-existing vessels. Coagulation factor X (FX) and it´s active form (FXa) have been demonstrated to possess antiangiogenic activity, although the mechanisms of action are currently unk